These Chicken Alfredo Roll-Ups turn a classic pasta favorite into a creamy, cheesy, and perfectly portioned dinner that feels both indulgent and comforting.
Each roll is packed with protein-rich chicken, layered in a velvety homemade Alfredo sauce, and topped with gooey melted mozzarella.
Despite its decadent flavor, it’s balanced with wholesome ingredients and ideal for quick family dinners or meal prep—easy to make, reheat, and enjoy all week long.
Chicken Alfredo Roll Ups
Equipment
- 1 Large pot (for boiling noodles)
- 1 colander (for draining noodles)
- 1 medium saucepan (for Alfredo sauce)
- 1 whisk (for stirring sauce)
- 1 9×13-inch baking dish
- 1 spatula or spoon (for spreading filling)
- 1 Measuring cup set
- 1 baking spray or brush (for greasing pan)
Ingredients
For the Roll-Ups:
- 8 lasagna noodles cooked al dente
- 2 cups shredded cooked chicken rotisserie or homemade
- 2 cups shredded mozzarella cheese
For the Garlic Alfredo Sauce:
- ¼ cup unsalted butter
- 2 cups heavy whipping cream 1 pint
- 4 oz cream cheese softened
- ½ teaspoon minced garlic
- 1 teaspoon garlic powder
- 1 teaspoon Italian seasoning
- ¼ teaspoon salt
- ¼ teaspoon black pepper
- 1 cup grated Parmesan cheese
Instructions
- Preheat Oven and Prepare Dish: Begin by preheating your oven to 350°F (175°C) so it’s ready once the roll-ups are assembled. Lightly grease a 9×13-inch baking dish with nonstick cooking spray or a thin layer of butter to prevent sticking. Setting the dish aside now allows you to focus on cooking the noodles and preparing the sauce without interruptions.
- Cook Lasagna Noodles Until Al Dente: Fill a large pot with water, season generously with salt, and bring to a rolling boil over high heat. Gently add the lasagna noodles, stirring occasionally to prevent them from sticking. Cook according to package directions until they are tender but still firm to the bite (al dente). Drain the noodles in a colander and rinse briefly under cold water to stop the cooking process. Lay the noodles flat on parchment paper or paper towels to prevent curling or sticking.
- Melt Butter and Prepare Sauce Base: In a medium saucepan, melt ¼ cup unsalted butter over medium heat. Once melted, add 2 cups of heavy whipping cream and 4 ounces of softened cream cheese. Whisk continuously until the mixture is smooth, creamy, and fully blended. The cream cheese helps thicken the sauce and gives it a velvety texture. Continue whisking until there are no lumps.
- Add Seasonings and Flavor Sauce: Once the sauce base is smooth, stir in ½ teaspoon minced garlic, 1 teaspoon garlic powder, 1 teaspoon Italian seasoning, ¼ teaspoon salt, and ¼ teaspoon black pepper. Whisk well to evenly distribute the seasonings. Continue cooking over medium heat until the mixture is aromatic and slightly thickened, making sure it does not burn.
- Incorporate Parmesan Cheese and Simmer: Gradually add 1 cup of grated Parmesan cheese while whisking constantly. Allow the sauce to simmer for 3–5 minutes, stirring frequently, until the cheese is fully melted and the sauce reaches a thick but pourable consistency. Remove from heat once smooth and creamy. This rich, flavorful Alfredo sauce will coat the roll-ups perfectly.
- Coat Baking Dish with Sauce: Pour approximately 1 cup of the prepared Alfredo sauce into the bottom of the greased baking dish. Spread it evenly with a spatula or spoon. This layer prevents the noodles from sticking and ensures each roll will bake in a pool of creamy, flavorful sauce.
- Assemble Roll-Ups with Filling: Lay one cooked lasagna noodle flat on a clean surface. Spread 2 tablespoons of Alfredo sauce evenly over the noodle. Top with 2 tablespoons of shredded chicken, followed by 3 tablespoons of shredded mozzarella cheese. Carefully roll the noodle from one short end to the other, keeping the filling contained. Repeat with all remaining noodles.
- Arrange Roll-Ups in Baking Dish: Place each rolled noodle seam-side down into the prepared baking dish. Arrange them snugly so they support each other during baking. Pour the remaining Alfredo sauce evenly over the top of all the rolls and sprinkle with the remaining mozzarella cheese to create a golden, bubbly topping.
- Bake Until Hot and Golden: Transfer the dish to the preheated oven and bake for 25–30 minutes, until the cheese is fully melted, bubbly, and slightly golden on top. The sauce will thicken further and the edges may brown lightly. Avoid overbaking to preserve the creamy texture and tender noodles.
- Rest and Serve: Once baked, remove the dish from the oven and allow it to rest for 5–10 minutes. This helps the sauce settle, making the rolls easier to serve without falling apart. Serve warm, optionally garnished with extra Parmesan, freshly cracked pepper, or a sprinkle of parsley. These Chicken Alfredo Roll-Ups pair beautifully with a crisp salad or garlic bread.
Notes
- Use rotisserie chicken or leftover roasted chicken to save time and add flavor.
- Ensure lasagna noodles are cooked al dente; overcooked noodles may tear when rolling.
- Allow the Alfredo sauce to thicken slightly before spreading—it helps the rolls hold together better.
- Feel free to mix cheeses like provolone or fontina with mozzarella for added richness.
- For extra flavor, sprinkle fresh herbs like parsley or basil over the baked rolls just before serving.
- These roll-ups are freezer-friendly: freeze unbaked or baked portions for a convenient make-ahead meal.
- To make a lighter version, substitute half-and-half for heavy cream or use part-skim mozzarella.
Chef’s Secrets for Perfect Rolls
The key to perfectly creamy Chicken Alfredo Roll-Ups lies in balance and technique.
Make sure the sauce is smooth, well-seasoned, and slightly thickened before assembling—this ensures each roll has a luxurious coating without becoming runny.
When spreading the filling, don’t overstuff; a modest amount of chicken and cheese allows the noodle to roll tightly without spilling.
Rolling the noodles seam-side down in the pan helps them hold their shape during baking.
Lastly, letting the dish rest after baking ensures the sauce settles, giving each slice a beautiful, uniform appearance.
Serving Suggestions for Maximum Enjoyment
These rolls are versatile and pair well with a variety of sides.
Serve with a simple green salad tossed in lemon vinaigrette to cut through the richness, or garlic bread for a comforting, indulgent combination.
Roasted or steamed vegetables like broccoli, asparagus, or carrots complement the creamy flavors and add a pop of color.
For entertaining, cut the rolls into smaller portions for bite-sized appetizers or serve as part of a buffet-style dinner.
A light sprinkle of fresh herbs or extra Parmesan elevates presentation and flavor.
Storage Tips for Freshness
Chicken Alfredo Roll-Ups store beautifully and are excellent for meal prep.
Keep leftovers in an airtight container in the refrigerator for up to 3–4 days.
To reheat, cover with foil and warm in the oven at 325°F (165°C) for 15–20 minutes until hot.
For longer storage, freeze the unbaked assembled rolls in a freezer-safe dish for up to 2 months.
Thaw in the refrigerator overnight and bake as directed, adding an extra 5–10 minutes if needed.
These roll-ups maintain their creamy texture even after freezing and reheating.
Frequently Asked Questions
1. Can I use pre-cooked rotisserie chicken?
Yes! Rotisserie chicken is a perfect shortcut. It adds flavor, saves time, and ensures your roll-ups are protein-packed. Simply shred and use it as directed in the recipe.
2. What if I don’t have heavy cream?
You can substitute half-and-half or a combination of milk and cream cheese, though the sauce may be slightly less rich. Whisk thoroughly to avoid lumps.
3. Can I make this recipe ahead of time?
Absolutely! Assemble the roll-ups in advance and refrigerate for several hours, or freeze unbaked rolls for up to two months. Bake them straight from the fridge or thawed from the freezer.
4. How do I prevent the noodles from breaking?
Cook the lasagna noodles just until al dente. Rinse them in cold water and lay them flat on a towel or parchment to prevent sticking. Avoid overfilling the rolls, and roll gently but firmly.
5. Can I add vegetables or other fillings?
Yes! Sautéed spinach, mushrooms, or roasted red peppers can be added for extra flavor and nutrition. Keep fillings moderate to maintain the ease of rolling and baking.
